Xylitol배합껌이 구강내 Streptococcus mutans와 Lactobacilli의 수애 미치는 영향에 관한 연구
Effect of Xylitol in Chewing Gum on Streptococcus mutans and lactobacilli
문혁수,
소속 상세정보
문혁수 ( ) - 서울대학교
KMID : 0355419950190020245
Abstract
The purpose of this study was to evaluate the effect of chewing gums containing sorbitol, xylitol and a mixture of xylitol and sorbitol on counts of Streptococcus mutnas and Lactobacilli, and salivary flow rate. Sixty school girls aging 12 to 13
participated. In this randomized, cross-over study. The three different chewing gums which containing 10 70% sorbitol, 2)35% sorbitol and 35% xylitol, and 3) 70% xylitol were tested. There experimental periods continues two weeks each and two
wash-out
periods between experimental periods. Stimulated saliva was collected for 5 minutes while students were chewing experimental gums to measure salivary flow rate. Dental plaque accumulated by no oral hygiene on the previous night and morning of
experimental day was collected to incubate Stretpococcus mutans. Collected saliva was used to incubate Lactobacilli. Stirnulated salivary flow rate and counts of Streptococcus mutans and of Lactobacilli were calculated according to experimental
gum
chewing groups and periods. Mean counts of Streptococcus mutans in all gum chewing group(sorbitol, xylitol and mixture of xylitol and sorbitol) were decreased(P<0.05). According to the Scheffe test for the multiple comparision, there were
significant
difference between sorbitol gum chewing groups and xylitol gum chewing group(P<0.05), and soritol gum chewing group and a mixture of xylitol and sorbitol gum chewing group(P<0.05). but there was no significant difference between a mixture of
xylitol and
sorbitol gum chewing group and xylitol gum chewing group(P>0.050). Mean counts of lactobacilli in all gum chewing groups were not decreased(P>0.05). Mean stimulated salivary flow rates of all gum chewing groups were not increased(P>0.05).
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